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Although infected persons can develop active TB disease at any time, the risk is highest 1–2 years after a new infection and decreases as time passes.
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The risk of developing active TB disease in infected persons with competent immune systems is approximately 10% over a lifetime.
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A person infected with both HIV and TB has a 10% yearly risk of developing TB disease.
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Note that HIV infection is not a homogeneous risk factor but is dependent variables including the underlying degree of immunosuppression, and CD4 count, among others.
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