Mental illness can be one of the more overlooked comorbidities with TB disease. People with TB can face strong stigma both from their communities and also internally. Certain anti-TB drugs including isoniazid and cycloserine have been linked to mental health problems.

People with mental illnesses and substance use disorders are more likely to:

• Be exposed to TB
• Develop TB disease
• Delay seeking care
• Miss doses
• Be lost to follow-up on treatment