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    • TB is the most common cause of death in people with HIV (PLWHIV) throughout the world and is considered an acquired immune deficiency syndrome (AIDS) defining illness.
    • It is estimated that one-third of the 35.3 million PLWHIV worldwide are co-infected with TB.
    • HIV infection greatly accelerates the development of TB disease due to a weakened immune system.
    • Active TB disease further suppresses the immune system of PLWHIV.
    • Therefore, when a patient has a TB and HIV co-infection, both diseases progress more rapidly.
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