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The key to TB diagnosis is a high index of suspicion coupled with proper diagnostic tests.
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Anyone who presents with signs or symptoms suggestive of TB, in particular cough (generally more than 2 weeks) should be further evaluated for possible TB disease.
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Cough is the most common symptom of PTB, but may not be present in up to a quarter of bacteriologically confirmed TB cases.
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Other signs or symptoms include hemoptysis, night sweats, fever, and weight loss.
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The most common way to detect PTB is by sputum smear microscopy. However, it is not a sensitive test and more rapid molecular tests such as Xpert/MTB/RIF should be used if available.
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