• Controlled clinical studies have shown that IPT reduces the risk of TB disease in HIV-positive individuals also infected with M. tuberculosis. (Ref)


• The evidence of M. tuberculosis infection is a positive TST.


• An additional benefit to IPT of a reduced risk of TB may be a reduced rate of progression of HIV infection.

Read more on WHO's Three I's approach which includes:

• IPT
• Intensified case finding for active TB
• Infection Control