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  • Cough alone is not sensitive enough to detect TB among HIV-positive persons (Ref.)

  • For this reason, it is particularly important to have a high index of suspicion for TB in an HIV-positive person who has any of the signs or symptoms compatible with TB.

  • Unrecognized MDR-TB is associated with such high mortality in patients with HIV, that all HIV-positive patients should receive an Xpert MTB/RIF test as the first diagnostic test when available, and their treatment response must be monitored closely even if the results are rifampicin sensitive.
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