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  • To detect cases of resistance early, check for MDR-TB risk factors in all TB patients and other people that belong to a high risk group.

  • Delayed diagnosis and treatment of DR-TB are major factors that contribute to poor treatment outcomes.

  • Refer these patients to a specialized MDR-TB center for diagnosis and treatment.

  • If a specialized MDR-TB center is not accessible, consult with the local TB control officials regarding patient referral and case management.

  • In some settings where drug resistance is known to be very high even among new patients, all persons to be evaluated for TB disease should ideally receive a rapid molecular test as a first diagnostic (or culture and DST) instead of smear microscopy.
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